What are the Causes of swollen hands Reviewed by Claire Sissons & Elaine K. Luo, MD Swelling happens when fluid builds up inside tissues. Numerous factors can cause it, including temperature change and underlying conditions. If swollen hands are due to a medical issue, treating it should resolve the swelling. A person may notice their fingers or hands appearing larger than usual. The skin may look puffy or shiny, and a dent may appear when a person presses the skin. Swelling in the hands often goes away without treatment. Making some lifestyle changes can help to reduce the frequency of swelling. Swollen hands may occur at certain times of day or have a link to particular activities. Making a note of when swelling happens can help pinpoint the cause. It may be a good idea to keep a record of the time of day and circumstances when the hands appear swollen. Some simple home remedies can reduce swelling in the hands. Treatment aims to encourage fluid to flow thro...